human heart tissue were subjected to SDS PAGE followed by western blot with FNab02227(DAAM1 antibody) at dilution of 1:500
IP Result of anti-DAAM1 (IP:FNab02227, 3ug; Detection:FNab02227 1:500) with mouse liver tissue lysate 8000ug.
Immunohistochemistry of paraffin-embedded human brain using FNab02227(DAAM1 antibody) at dilution of 1:100
Background
Binds to disheveled(Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.